Using our C1 and Biomark HD systems, the workflow for single-cell miRNA expression profiling provides an easy and reliable way to automatically capture and process individual live cells for routine miRNA analysis. Studying miRNA expression at the single-cell level offers greater insight into the differences between cells in the same population. These small, noncoding RNAs regulate thousands of human protein-coding genes that are involved in biological processes-such as differentiation, development and cell cycle management-as well as illnesses including cancer and cardiovascular disease.Ī single miRNA may regulate several biological systems, introducing cell-to-cell variability and making it difficult to reliably interpret and predict miRNA targets. MicroRNAs (miRNAs) regulate mRNA expression by mRNA degradation and gene silencing. Measure expression levels of genes, alleles and spliced variantsĬompare tissue or cell type expression levelsĭiscover new transcripts and gene fusions With the C1 single-cell mRNA sequencing workflow, you can:Īutomatically process up to 800 individual cells per runĬharacterize the cellular makeup of a tissue and compare the abundance of specific cell types among samples This tool can also uncover the genetic programs that drive development and the mechanisms underlying cellular responses to the environment, disease and drug response. Single-cell mRNA sequencing on the C1™ system can reveal the unique cellular makeup of tissues, including the identification of important, rare cell populations that cannot be identified by bulk analysis. Researchers are analyzing the transcriptome at greater resolution to uncover new mechanisms of cell development, metabolism and disease.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |